The course will cover the aspects of the composition and function of the intestinal microbiota from birth, during life and the ageing period, how it might be influenced by diet and disease, and host-microbe crosstalk. Sequencing techniques will be introduced for the study the microflora and compared to biochemical methods. Novel findings will be discussed by lecturers in the research front-line on the translational topics of normal flora in relation to inflammatory bowels diseases (IBD), irritable bowels syndrome (IBS) celiac disease, reumatological and neurophysiological diseases. The course will be suitable for clinical and pre-clinical PhD students and researchers where the microbiota is of significance, including areas such as allergy, asthma, systemic autoimmune diseases, cardiovascular diseases, obesity, rheumatology, neurophysiological disturbances such as autism spectrum disorders, chronic fatigue, nutrition - including effects of pre- and probiotics, diabetes, metabolic syndrome, infectious diseases and bioinformatics. The course replaces the previous course 2300.