The epigenome: an interface between nutrition and health

Learning outcomes : Following the completion of the course the students will be able to describe the basic principles of epigenetic regulation and how this relates to metabolism and human diseases, such as cancer and diabetes. The students will also be able to design experiments for studying chromatin marks and to critically evaluate results obtained with these techniques.

Contents of the course : The course covers the molecular mechanism of epigenetic regulation and how chromatin based processes are linked to human diseases. Particular attention will be paid to the crosstalk between chromatin marks and metabolism. Furthermore, we will discuss the regulation of these processes during the circadian cycle and their deregulation in cancer and diabetes mellitus. Speakers of the course will include the course organisers and several well­known international researchers dedicated to research on various aspects of chromatin.

Teaching and learning activities : The learning activities used in the course include lectures, research seminars and research article presentation by the students. Every student will present a recent publication in the form of a journal club. Students will also be encouraged to actively participate in the course. There will be substantial time for discussions after the lectures and research seminars.